List of Steroids by Half-Life
For question about pct you can calculate it yourself with the half-life list or use this calculator. The result is a faster onset of gains and performance and physique changes compared to the standard dosing method. This means that the anabolic steroid in question would express a longer half-life in the body.
First Things First – Understanding Anabolic Steroids
There are several different definitions of what a half-life is depending on the area of scientific study , but although there are different definitions, they only differ ever so slightly. For instance, the half-life of Anavar is approximately nine to 10 hours. Injectable anabolic steroid half-lives generally range from 24 hours to as long as 15 days or more, depending on the anabolic steroid used and whether or not it is esterified and what kind of ester is bound to it. In addition to the higher bodybuilding dosage, the injections must be administered much more frequently. Another 14 days from then, i. The drug is released from the injection site into the bloodstream days or hours after injection.
So here in simple terms you can read and hopefully understand all about steroid half life's and what this term means.
Basically every drug has a half life, steroids included. If for example, you were to inject mg of Decadurabolin once weekly, for 6 weeks, how would you know when you were "off"? Would you be "off" when you had finished your last dose? You would be able to calculate this from the half life of Deca.
The half life of Deca is around 14 days. This means that 14 days from your last shot of mg of Deca, your blood levels of Deca will contain mg of the steroid. Another 14 days from then, i. This amount then keeps halving every 14 days. Therefore you can clearly see that when you finish your cycle, even though you are not putting any steroids into your body, you may think that you are now "off", however you still have, and will still have for some time after your last dose, "active" blood levels of the steroid.
Therefore you can plan what to use, how long for, and how long off your cycle, based on these half life's. Below a list of half-life's of the most commonly used steroids, esters and ancillary compounds. The general definition of a half-life is the same. However, the dictionary definition of half-life in physics is as follows: The dictionary definition of half-life as it pertains to biology is as follows: Also called biological half-life. The time required for the activity of a substance taken into the body to lose one half its initial effectiveness.
The general or informal dictionary definition of half-life is as follows: A brief period during which something flourishes before dying out. Different dictionary definitions will differ from one another, but the general concept of a half-life as it pertains to biology and pharmacology is: For example, if an individual injects mg of Testosterone Propionate, which exhibits a half-life of 4. The concept of steroid half-lives is extremely important to understand, because it allows the individual to understand the amount of time a particular anabolic steroid or drug is actively remaining in the body after administration.
This will assist the individual in better planning and organizing his or her cycle appropriately, and understand how to properly time the administration of the anabolic steroids so as to achieve the most effective, comfortable, and safe cycle. The proper understanding of half-lives is very important for the understanding of how long it might take before a particular compound reaches peak optimal blood plasma levels in the body.
This is very important, because the results and gains experienced from anabolic steroids do not normally occur until these peak optimal blood plasma levels are achieved in the body. The importance of understanding steroid half-lives is also an issue of safety. Without a proper and thorough understanding of the half-live of a drug, it is very possible for an individual to improperly administer the drug and result in self-injury, harm, or even death.
Most of the time, improper administration timing according to the half-lives of different steroids used can result in a very uncomfortable experience, which will most often increase the severity and incidence of side effects that occur. The understanding of steroid half-lives is one of the very first concepts that should be grasped by any individual looking to use anabolic steroids.
Anabolic steroid half-lives are affected by a few different factors, the three primary of which are: The route of administration has a very significant impact on the half-life of an anabolic steroid.
There are two primary routes of administration for anabolic steroids: A third route would be transdermal patches, gels, or creams, which are methods of absorption through the skin. However, anabolic steroid use for the purpose of physique and performance enhancement are almost always achieved through either oral administration, or injection. There are other less popular methods of administration as well that have been used, such as implantation pellets and sublingual and nasal applications, though they are far too rare to bother covering.
The oral route of administration grants some of the shortest steroid half-lives among the different compounds. This is due to the fact that the vast majority of anabolic steroids are un-esterified, and are ingested in their pure and immediately active format. Because the oral route of administration presents no delay in the release of the anabolic steroid to the bloodstream, the hormones are instantaneously active and playing an active role in the body as soon as they hit the bloodstream after they make the first pass through the liver.
Although these oral anabolic steroids undergo a first pass through the liver, the amount of metabolism through the hepatic liver pathway does not slow down the release of the hormones into the bloodstream by much. In fact, one of the reasons as to why oral steroid half-lives are much shorter than injectable steroid half-lives is because of the immediate exposure to liver metabolism, which facilitates faster metabolism and elimination of the hormone in and out of the body.
Oral anabolic steroid half-lives generally range from 4 hours to 48 hours, depending on the anabolic steroid used. Injectable anabolic steroids consist of two different types: The second type are water-based injectables, known as suspensions, where the hormone is suspended in microcrystals that are in a water base.
Once water-based suspensions are injected into muscle tissue, the microcrystals are slowly dispersed and released into the bloodstream into circulation.
Injectable steroid half-lives are, for the most part, significantly longer than oral anabolic steroid half-lives. The reason for this is because of the nature of oil-based and water-based injections, which are designed to form a depot in the muscle tissue they are injected in, after which a slow release from the injection site into the bloodstream occurs in the hours or days after the injection.
This extends the steroid half-lives quite significantly, but it is actually an additional factor that extends the injectable steroid half-lives even more: Nearly all anabolic steroids, especially oil-based, are esterified so as to deliberately extend their half-life and to make them more fat soluble in order to better dissolve in the carrier oil.
The only exception to this is Testosterone Suspension and Winstrol Stanozolol , both of which are injectable anabolic steroids that are not esterified at all. Injectable anabolic steroid half-lives generally range from 24 hours to as long as 15 days or more, depending on the anabolic steroid used and whether or not it is esterified and what kind of ester is bound to it. Esterification is perhaps the most influential contribution to the different steroid half-lives.
This type of bonding is known as esterification also known as an ester bond. The carboxylic acids that are esterified to an anabolic steroid are of different and varying lengths, normally in the form of a carbon chain. Longer ester bonds will require more time for these enzymes to free the hormone from the ester. But once the anabolic steroid hormone is broken free from the ester, what remains is a pure and active anabolic steroid that is free to do its work in the body.
For example, pure and un-esterified Testosterone expresses a half-life of approximately 4 — 24 hours, but Testosterone Propionate expresses a half-life of 4. Esterification was deliberately devised by scientists back in the s in order to deliberately extend the half-life of different anabolic steroids.
Esterification successfully extends the half-life of anabolic steroids to lengths that would require far less frequent injections, and therefore more comfortable injection schedules for patients. For example, some oral anabolic steroids exhibit a half-life of 4 hours, while others will exhibit a half-life of 24 hours.
This means that the anabolic steroid in question would express a longer half-life in the body. Ultimately, however, all drugs, anabolic steroids, foods, chemicals, and compounds eventually undergo metabolism and elimination from the body — there is no such anabolic steroid or drug that will last forever in its active state in the body.
Iamges: half life of anabolic steroids
The same might not be said for Winstrol Stanozolol , which expresses a half-life of 9 hours in the body, and therefore individuals could easily get by with ingesting their full dose all at once. This means that the anabolic steroid in question would express a longer half-life in the body.
Below a list of half-life's of the most commonly used steroids, esters and ancillary compounds. The second kind is water-based injectables called suspensions, where the hormone is frozen in water-based microcrystals.
A third route would be transdermal patches, gels, or creams, which are methods of absorption through the skin. Esterification was deliberately devised by scientists back in the s in order to deliberately extend the half-life of different anabolic steroids. Another 14 days from then, i. This means that the anabolic steroid in question would express a longer half-life in the body. But Deca has a long ester, as well as being oil-based, so that's going half life of anabolic steroids be a slow gradual release.
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